Simulation the interaction range of Alpha and 7Li particle in human tissues on BNCT therapy

Abstract

This paper examines the function of particle therapy, a novel form of radiation therapy (RT) that has gained popularity and quick advancement in recent years, in interdisciplinary care. Proton beam therapy (PBT), carbon-ion beam therapy (CIBT), and boron neutron capture therapy (BNCT) are the three particle therapies that are currently used to treat cancer. One special feature of boron neutron capture therapy (BNCT) is its ability to selectively irradiate tumor cells with heavy particles. Even when cancer and normal cells are mixed together at the tumor edge, BNCT can still create significant dose gradients between the two types of cells. This characteristic allows pre-irradiated locally recurrent cancers to be treated with BNCT. It is yet unclear, though, whether thermal neutron irradiation of the region will cause the two heavy particles that result from the BNCT reaction to target the malignant cells more specifically. This paper's second section describes the simulation that SRIM utilized to determine the interaction range between two heavy particles, alpha and 7Li particles, in human tissues during BNCT treatment. Based on this simulation, we discovered that the energy generated by BNCT therapy can be largely absorbed by the pathogen, leading to successful treatment outcomes and avoiding harm to other healthy tissues in the human body. This effectively shows that BNCT therapy is stable and feasible.