The Mechanism of Natural Active Substances in Chicory for Treating Diabetes
DOI:
https://doi.org/10.54097/nemsk319Keywords:
Chicory Acid, Hypoglycemic, Diabetes, Insulin, Mechanism Analysis.Abstract
Diabetes mellitus is a prevalent and frequent chronic metabolic disease characterized by hyperglycemia. While conventional drugs are available, their use is limited due to side effects. Natural products of medicinal plants are gradually recognized by countries all over the world because of their good curative effect and small side effects. The aims of this article are to discuss the hypoglycemic effects of chicory’s natural active substances and their mechanisms in diabetes treatment. The results show that natural active substances in chicory exhibit significant hypoglycemic effects. Chicory natural active substances can play a certain hypoglycemic role in diabetes through different ways. The results of data analysis indicate that that the existence of natural active substances in chicory includes three mechanisms of action: promoting insulin secretion, affecting insulin signaling pathway and promoting glucose uptake and other anti-diabetic activities. This article can provide insights for further pharmacological research on chicory’s natural active substances in diabetes treatment.
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