Role of PPAR γ in Immune Cells

Yuxuan Hao; Xinlong Zhai; Yinchao Ma; Yuan Liu; Ziyuan Wang; Ming Chu

doi:10.54097/j181cd43

Authors

Yuxuan Hao
Xinlong Zhai
Yinchao Ma
Yuan Liu
Ziyuan Wang
Ming Chu

DOI:

https://doi.org/10.54097/j181cd43

Keywords:

PPARγ, macrophages, neutrophils, NK cells, T cells, B cells, metabolism, differentiation.

Abstract

Peroxisome proliferators - activated receptor γ (PPAR γ), which is a type of nuclear receptor, exhibits extensive expression across multiple biological fields. As a transcription factor, it plays a role in regulating gene expression and influencing diverse physiological processes, with a particular emphasis on immune cells. In this article, the biological functions of PPAR γ within macrophages, neutrophils, NK cells, T cells (including CD8+T, Th2, Th9, Th17, and Treg cells), and B cells are investigated.

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