Non-Invasive Wearable Biosensors for Detection of Sweat and ISF in Daily Life

Abstract

The potential of wearable sensors to non-invasively continuously monitor single or multiple objects within biological fluids such as sweat, saliva, interstitial fluid, and tears has been widely recognized. There have been recent breakthroughs in optical, electrical, piezoelectric and iontophoresis-based sensors. Targeted monitoring of glucose, alcohol, cortisol and lactic acid can be achieved. There are also some works devoted to multi-source sensor integration and the construction of multi-analyte sensors. Various research efforts are devoted to sensor miniaturization, the development of flexible materials, and the improvement of reliability. Although the current non-invasive wearable sensors for sweat and interstitial fluid have proven to have high potential, the relationship between the chemical components in sweat and interstitial fluid and the components in blood still needs more experimental verification, and their application in daily life The stability and accuracy of live tense has not been proven. It is necessary to conduct a detailed and in-depth exploration of the connection between various monitoring indicators and human health to promote the credibility and recognition of sensors in daily society. Non-invasive wearable sensors for sweat and interstitial fluid will have a profound impact on people's daily lives and health monitoring.