Stem cell and organoid modeling in cancer study

Tingyi Li

doi:10.54097/30jjys67

Authors

Tingyi Li

DOI:

https://doi.org/10.54097/30jjys67

Keywords:

Stem cell, Cancer stem cell, Tumor microenvironment, 3D printing, Heterogeneous.

Abstract

Stem cells are of many types and play important roles in the development and repair of tissue. The first time when we discovered the stem cell, different types of stem cells were brought into our vision—such as embryonic stem cells; and somatic stem cells. Stem cell therapy is rising rapidly these days and has become an important treatment in the medical system. They have been tried to apply in different kinds of disease treatments such as cancer, nerve injury, ocular diseases, etc. But besides these, there are some other special stem cells such as cancer stem cells (CSCs). CSCs are the cells that drive the growth of the tumor and often depend on the tumor microenvironment. When they are combined with 3D printing technology and organ transplantation, they can do more things like simulating the organ’s environment figuring out how the disease and drugs work, and making the product of the stem cell therapy apply in the human body. And the combination of stem cell therapy and 3D printing technology is a rising way for us to study and treat this disease. However, some difficulties and hurdles are still on the road to development, we still need to focus on how to make them fully functional in the human body and the issue of medical ethics.

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