Research on the Application of Probiotic Products Based on New Processing Technologies

Yuqi Bi

doi:10.54097/fd4grf79

Authors

Yuqi Bi

DOI:

https://doi.org/10.54097/fd4grf79

Keywords:

Probiotics, Processing Technology, Biological Activity, Application.

Abstract

Probiotics are beneficial to human health. However, traditional processing methods are highly likely to destroy the viability of probiotics, so there is an urgent need for new processing technologies to handle probiotics. Currently, there are relatively few review articles on new processing technologies in probiotic products. This article conducts a systematic evaluation of the relevant literature on the application of new processing technologies in probiotic products. During the retrieval process, keywords closely related to the theme, such as "probiotics", "processing technology", "viability", and "high - temperature sterilization", are focused on, and the retrieval is carried out with the help of databases such as Web of Science, Google Scholar, and PubMed. This paper deeply explores the application of new processing technologies in probiotic products from dimensions such as principles, advantages, challenges and improvements, and applications. The research finds that new processing technologies are expected to promote the expansion of probiotic products into more fields, which is of great significance for the further development of the probiotic industry.

Downloads

Download data is not yet available.

References

[1] Oniszczuk A, Oniszczuk T, Gancarz M, Szymańska J. Role of gut microbiota, probiotics and prebiotics in the cardiovascular diseases [J]. Molecules. 2021, 26(4):1172.

[2] Seddik HA, Bendali F, Gancel F, et al. Lactobacillus plantarum and its probiotic and food potentialities [J]. Probiotics Antimicrob Proteins, 2017, 9(2):111-122.

[3] Camilleri M. Human intestinal barrier: effects of stressors, diet, prebiotics, and probiotics [J]. Clinical and Translational Gastroenterology, 2021, 12(1): e00308.

[4] Mazziotta C, Tognon M, Martini F, et al. Probiotics mechanism of action on immune cells and beneficial effects on human health [J]. Cells, 2023, 12(1):184.

[5] Liu BN, Liu XT, Liang ZH, et al. Gut microbiota in obesity [J]. World Journal of Gastroenterology, 2021, 27(25):3837-3850.

[6] Li P, He X, Feng E, et al. Lactobacillus acidophilus JYLA-126 ameliorates obesity-associated metabolic disorders by positively regulating the AMPK signaling pathway through the Gut-Liver Axis [J]. Probiotics and Antimicrobial Proteins, 2025, 17(1):62-80.

[7] Yang Z, Wang Q, Liu Y, et al. Gut microbiota and hypertension: association, mechanisms and treatment [J]. Clinical and Experimental Hypertension, 2023, 45(1):2195135.

[8] Penha Rodrigues Pereira E, Silva da Graça J, Manfrinato Ferreira B, et al. What are the main obstacles to turning foods healthier through probiotics incorporation? a review of functionalization of foods by probiotics and bioactive metabolites [J]. Food Research International, 2024, 176:113785.

[9] Payne J, Bellmer D, Jadeja R, et al. The potential of Bacillus species as probiotics in the food industry: A Review [J]. Foods. 2024, 13(15):2444.

[10] Chang T, Zhao G. Ice Inhibition for cryopreservation: materials, strategies, and challenges[J]. Advanced Science. 2021, 8(6):2002425.

[11] Bassi A, Sharma G, Deol PK, et al. Preclinical potential of probiotic-loaded novel gelatin-oil vaginal suppositories: efficacy, stability, and safety studies [J]. Gels, 2023, 9(3):244.

[12] Wang C, Zheng H, Liu T, et al. Physiochemical properties and probiotic survivability of symbiotic corn-based yogurt-like product [J]. Journal of Food Science, 2017, 82(9):2142-2150.

[13] Łętocha A, Miastkowska M, Sikora E. Preparation and characteristics of alginate microparticles for food, pharmaceutical and cosmetic applications [J]. Polymers (Basel). 2022, 14(18):3834.

[14] Paula DA, Martins EMF, Costa NA, et al. Use of gelatin and gum arabic for microencapsulation of probiotic cells from lactobacillus plantarum by a dual process combining double emulsification followed by complex coacervation [J]. International Journal of Biological Macromolecules, 2019, 133:722-731.

[15] Ribeiro LLSM, Araújo GP, de Oliveira Ribeiro K, et al. Use of encapsulated lactic acid bacteria as bioprotective cultures in fresh brazilian cheese [J]. Brazilian Journal of Microbiology, 2021, 52(4):2247-2256.

[16] Feng K, Huang RM, Wu RQ, et al. A novel route for double-layered encapsulation of probiotics with improved viability under adverse conditions [J]. Food Chemistry, 2020, 310:125977.

[17] Tian S, Xue X, Wang X, et al. Preparation of starch-based functional food nano-microcapsule delivery system and its controlled release characteristics [J]. Frontiers in Nutrition, 2022, 9:982370.

[18] Hou W, Li J, Cao Z, et al. Decorating bacteria with a therapeutic nanocoating for synergistically enhanced biotherapy [J]. Small, 2021, 17(37): e2101810.

[19] Sevenich R, Kleinstueck E, Crews C, et al. High-pressure thermal sterilization: food safety and food quality of baby food puree [J]. Journal of Food Science, 2014, 79(2):M230-M237.

[20] Mis-Solval KE, Jiang N, Yuan M, et al. The effect of the ultra-high-pressure homogenization of protein encapsulants on the survivability of probiotic cultures after spray drying [J]. Foods, 2019, 8(12):689.

[21] Jarzynka S, Strom K, Barbarska O, et al. Combination of High-Pressure processing and Freeze-Drying as the most effective techniques in maintaining biological values and microbiological safety of donor milk [J]. International Journal of Environmental Research and Public Health. 2024, 21(7):822.

[22] de Oliveira Filho JG, Duarte LGR, Bonfim DO, et al. Shaping the future of functional foods: using 3D printing for the encapsulation and development of new probiotic foods [J]. Probiotics and Antimicrob Proteins, 2025, 17(3):1295-1307.

[23] Li W, Wang M, Ma H, et al. Stereolithography apparatus and digital light processing-based 3D bioprinting for tissue fabrication [J]. iScience, 2023, 26(2):106039.

[24] Zhang Y, Zhou C, Tian B, et al. 3D printed spiral tube-like cellulose scaffold for oral delivery of probiotics [J]. Science Advances, 2024, 10(34): eadp3654.

[25] He H, Zhang X, Sheng Y. Enteric-coated capsule containing β-galactosidase-loaded polylactic acid nanocapsules: enzyme stability and milk lactose hydrolysis under simulated gastrointestinal conditions [J]. Journal of Dairy Research, 2014, 81(4):479-484.

[26] Asgari S, Pourjavadi A, Licht TR, et al. Polymeric carriers for enhanced delivery of probiotics [J]. Advanced Drug Delivery Reviews, 2020, 161-162:1-21.

[27] Wang L, Hu J, Li K, et al. Advancements in gene editing technologies for probiotic-enabled disease therapy [J]. iScience, 2024, 27(9):110791.

[28] Kim K, Choe D, Song Y, et al. Engineering bacteroides thetaiotaomicron to produce non-native butyrate based on a genome-scale metabolic model-guided design [J]. Metabolic Engineering, 2021, 68:174-186.

[29] Wang Y, Wu J, Lv M, et al. Metabolism characteristics of lactic acid bacteria and the expanding applications in food industry [J]. Frontiers in Bioengineering and Biotechnology, 2021, 9:612285.